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Certara Simcyp Simulator

The Most Sophisticated Platform for Mechanistic PBPK Modeling and Simulation.

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Overview

The Simcyp Simulator is a leading physiologically based pharmacokinetic (PBPK) modeling platform used by pharmaceutical scientists to predict the fate of drugs in the body. It allows for the simulation of drug behavior in diverse virtual populations, helping to optimize drug development strategies and inform regulatory decisions.

✨ Key Features

  • PBPK Modeling for Small and Large Molecules
  • Virtual Patient Populations
  • Drug-Drug Interaction (DDI) Predictions
  • Pediatric and Special Population Simulations
  • Formulation and Biopharmaceutics Modeling
  • Regulatory Acceptance

🎯 Key Differentiators

  • Extensive library of validated compound and population models.
  • Strong emphasis on mechanistic modeling and scientific rigor.
  • Widely accepted by regulatory agencies worldwide.

Unique Value: A scientifically rigorous and regulatory-accepted platform for predicting drug pharmacokinetics, enabling more efficient and ethical drug development.

🎯 Use Cases (4)

First-in-human dose selection Clinical trial design and optimization Label extension and justification for clinical trial waivers Formulation development

✅ Best For

  • Informing drug labels and supporting regulatory submissions through the use of PBPK modeling in place of clinical studies.

💡 Check With Vendor

Verify these considerations match your specific requirements:

  • Early-stage drug discovery without a need for detailed pharmacokinetic predictions.

🏆 Alternatives

Simulations Plus GastroPlus PK-Sim

Offers a more extensive and validated library of populations and drug models, particularly for special populations.

💻 Platforms

Desktop

✅ Offline Mode Available

🔌 Integrations

Other Certara software (e.g., Phoenix WinNonlin) R

🛟 Support Options

  • ✓ Email Support
  • ✓ Phone Support
  • ✓ Dedicated Support (Standard tier)

🔒 Compliance & Security

✓ GDPR

💰 Pricing

Contact for pricing

✓ 14-day free trial

Free tier: NA

Visit Certara Simcyp Simulator Website →